This section provides an overview of the coagulation assays currently
in clinical use and under development to diagnose and monitor
treatment effectiveness in patients with selected bleeding disorders.
Clot-based activity assays
Clot-based activity assays provide a global assessment of coagulation
function and are most commonly used to assess patients with suspected
bleeding abnormalities or to monitor anticoagulant therapy.
Global coagulation assays can be used to characterise some
haemostatic disorders and to monitor the effects of treatment. Methods
include viscoelastic assays, thrombin generation assays and
transmittance waveform analysis, a variation on one-stage clot assays.